Product Name: CrkII Antibody#3492
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 150725-87-4
Product: Ro 46-2005
Specificity Sensitivity: CrkII Antibody detects endogenous levels of CrkII protein. This antibody does not cross-react with related proteins.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Trp169 of human CrkII protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: CrkII, a cellular homologue of v-Crk, belongs to a family of adaptor proteins with an SH2-SH3-SH3 domain structure that transmits signals from tyrosine kinases (1). The primary function of Crk is to recruit cytoplasmic proteins in the vicinity of tyrosine
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22695116?dopt=Abstract
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