Product Name: CYP2D6 (D5A6X) Rabbit mAb#73867
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 329218-11-3
Product: Quetiapine sulfoxide (dihydrochloride)
Specificity Sensitivity: CYP2D6 (D5A6X) Rabbit mAb recognizes endogenous levels of total CYP2D6 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val408 of human CYP2D6 protein.
Background: Cytochrome P450 2D6 (CYP2D6) is a member of the cytochrome P450 superfamily of enzymes. CYP2D6 is located in the endoplasmic reticulum where it oxidizes substrates such as drugs and environmental chemicals (1,2). CYP2D6 metabolizes more than 25% of curren
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21887332?dopt=Abstract
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