Product Name: CYLD Antibody#4495
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 103476-89-7
Product: Leupeptin (hemisulfate)
Specificity Sensitivity: CYLD Antibody detects endogenous levels of total CYLD protein.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His334 of human CYLD protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: CYLD is a cytoplasmic deubiquitinating enzyme encoded by a tumor suppressor gene altered in individuals diagnosed with cylindromatosis, a genetic condition characterized by benign tumors of skin appendages (1,2). Functional CYLD deubiquitinase regulates i
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24415942?dopt=Abstract
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