Product Name: CUL3 Antibody#2759
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 937039-45-7
Product: Pimelic Diphenylamide 106
Specificity Sensitivity: CUL3 Antibody detects endogenous levels of total Cullin-3.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu750 of human Cullin-3. Antibodies are purified by protein A and peptide affinity chromatography.
Background: CUL3 (Cullin-3) is a member of the cullin-based ubiquitin ligase family. By interacting with Hrt1 and BTB domain containing proteins, the complex functions as a CUL3-based E3 ligase to bring specific substrates to ubiquitinylation and degradation (1). The
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25999520?dopt=Abstract
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