Product Name: Arrestin 1/S-Arrestin Antibody#11828
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 610798-31-7
Product: Icotinib
Specificity Sensitivity: Arrestin 1/S-Arrestin Antibody recognizes endogenous levels of total Arrestin 1/S-Arrestin protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala163 of human Arrestin 1/S-Arrestin protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Arrestin proteins function as negative regulators of G protein-coupled receptor (GPCR) signaling. Cognate ligand binding stimulates GPCR phosphorylation, which is followed by binding of arrestin to the phosphorylated GPCR and the eventual internalization
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24126110?dopt=Abstract
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