Product Name: Anoctamin 1 (D1M9Q) Rabbit mAb#14476
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 74681-68-8
Product: Nuclear yellow
Specificity Sensitivity: Anoctamin 1 (D1M9Q) Rabbit mAb recognizes endogenous levels of total Anoctamin 1 protein. An unidentified band is detected around 30 kDa in some tissues.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala976 of human anoctamin 1 protein.
Background: Anoctamin 1, also called TMEM16A for Transmembrane Member 16A, is a plasma membrane calcium-activated chloride channel (1). It is essential for chloride secretion from epithelial tissues (2), and has been shown to be a specific marker for cells of Cajal (
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22275873?dopt=Abstract
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