Product Name: ASK1 (D11C9) Rabbit mAb#8662
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 17673-25-5
Product: Phorbol
Specificity Sensitivity: ASK1 (D11C9) Rabbit mAb recognizes endogenous levels of total ASK1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile280 of human ASK1 protein.
Background: Apoptosis signal-regulating kinase 1 (ASK1), a MAP kinase kinase kinase, plays essential roles in stress-induced apoptosis (1,2). ASK1 is activated in response to a variety of stress-related stimuli through distinct mechanisms and activates MKK4 and MKK3,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25973684?dopt=Abstract
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