Oduce the new LAI antipsychotic right after the discontinuation of the present LAI FGA or

Oduce the new LAI antipsychotic right after the discontinuation of the present LAI FGA or LAI SGA (when the time since the last injection corresponds towards the interval involving two injections). In 2nd line technique, the switch from the present LAI FGA or LAI SGA to the new LAI SGA is advisable directly soon after having given an oral test dose on the newly introduced SGA LAI so as to remove any hypersensitivity. The initial dose for the oral form or for the new LAI SGA will correspond (if possible) to an equivalent dose of the previous LAI FGA or LAI SGA (1st line technique).Sensible procedures for the introduction and for the injection remindersIn order to assist together with the acceptance and understanding on the benefits of an LAI remedy, it isLlorca et al. BMC Psychiatry 2013, 13:340 http:www.biomedcentral.com1471-244X13Page 8 ofFigure 3 Graphic results of the question about benefitrisk balance for LAI FGA and LAI SGA in schizophrenic patients.unanimously advisable by the specialists (order Naringin technique of choice) to convey towards the patient particular information concerning each the advantages and inconveniences from the FGA and SGA LAI, that are getting regarded as, within the framework of shared decisionmaking. Through the introduction of the remedy, initiation of the LAI kind is encouraged prior to the end of a full-time hospitalization for an acute episode (strategy of choice). Introduction of LAI antipsychotics may also be deemed for the duration of outpatient care (as 2nd line technique). The 1st line approach of performing the injections through the upkeep remedy in outpatients is to coordinate the follow-up psychiatric consultations using the dates with the injections. The injections also can be performed by a nurse within a hospital day care unit or at home (as 1st line tactic).Table eight Benefitrisk ratio for LAI FGA and LAI SGA in bipolar disorderPrevention of manic recurrence 1st-line remedy Prevention of depressive recurrence -Note: these injection procedures aren’t applicable to olanzapine pamoate as this therapy calls for precise post-injection monitoring within a hospital. To be able to boost patient compliance, it really is advised that the following reminder tactics are put in place: 1st line methods, working with telephone reminders and agenda given towards the patient (follow-up diary). 2nd line techniques, by letter or ultimately by text messages. The prevention of nearby complications calls for the injections to be performed: deep intramuscularly (gluteal or deltoid muscle) (tactic of selection). by changing the injection web site every single time (as 1st line technique). by proposing a nearby transdermal anaesthetic (cream or patch) just before the injection so that you can decrease the discomfort at the injection site (as 2nd line method).Precise therapeutic tactics in accordance with the psychiatric disorder or its co-morbidities Schizophrenia and delusional chronic disorder2nd-line In monotherapy or in combination Often in combination treatment using a mood stabilizer with a mood stabilizer Risperidone LAI Olanzapine pamoate Risperidone LAI Olanzapine pamoateAcute psychotic episode with LAI FGA or LAI SGA therapy The relevant question in the survey with all the experts’ answers are given in Figure four.Llorca et al. BMC PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21310317 Psychiatry 2013, 13:340 http:www.biomedcentral.com1471-244X13Page 9 ofFigure four Graphic benefits with the query about therapeutic methods for the duration of an acute psychotic episode.- In the acute phaseSeveral therapeutic adaptations are advisable as 1st line tactics: Optimization of.