Background: An early prediction of poor outcomes is essential in the management of patients after a liver resection. The aim of this study was to evaluate the role of selected…
**Background** Tumor hypoxia is a hallmark of solid tumors, often leading to the overexpression of specific enzymes that regulate pH balance to support cancer cell survival and progression. Carbonic anhydrases…
Acute ischemic stroke remains a leading cause of disability and death worldwide, with treatment efficacy heavily dependent on timely intervention and patient-specific factors. The SENTIS trial, a large-scale randomized study…
**Background** Acne vulgaris is a common inflammatory skin condition characterized by the proliferation of Cutibacterium acnes (formerly Propionibacterium acnes). The management of moderate to severe acne often requires the use…
Primary localized cutaneous amyloidosis (PLCA) is a chronic dermatological condition characterized by the deposition of amyloid material in the upper dermis, leading to persistent pruritus, skin hyperpigmentation, and lichenification. While…
**Background** Hemoglobinopathies, such as sickle cell disease and $\beta$-thalassemia, are genetic blood disorders characterized by the abnormal structure or production of hemoglobin. A promising therapeutic strategy for these conditions involves…
The magnocellular neurosecretory cells (MNCs) of the hypothalamic supraoptic nucleus play a central role in maintaining fluid homeostasis by releasing vasopressin and oxytocin in response to changes in extracellular osmolality.…
**Background** Bacterial infections remain a significant global health challenge, particularly with the rise of antimicrobial resistance. Acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections are common…
Recent studies have revealed that Arf, a bona fide tumor suppressor gene located within the Cdkn2a locus, plays a critical role in mouse eye development. In developing mouse eyes, transforming…
Endometriosis is a chronic gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity, most commonly on the peritoneum. This ectopic tissue induces a persistent inflammatory environment,…