**Background** Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and the accumulation of amyloid-beta plaques and tau tangles. Oxidative stress is a hallmark of…
**Background** Casein kinase 1 (CK1) is a family of serine/threonine kinases that play critical roles in various cellular processes, including signal transduction and the regulation of the biological clock. Among…
**Background** The regulation of the autonomic nervous system is critical for maintaining homeostasis, particularly in the control of vascular tone and organ function. The sympathetic nervous system utilizes vasoconstrictor neurotransmitters…
**Background** The regulation of circadian rhythms and the modulation of serotonergic pathways are critical for maintaining neurological health and emotional stability. Melatonin receptors, specifically MT1 and MT2, play a pivotal…
To bridge the gap between in vitro cell culture and clinical relevance, this protocol establishes a three-dimensional (3D) skin equivalent model using ECM-activated collagen-GAG scaffolds seeded with diabetic foot ulcer…
The pursuit of durable electrocatalysts for clean energy technologies demands a deep understanding of degradation mechanisms at the nanoscale. In this study, we present a rational design strategy for Pd@Pt…
This study demonstrates the power of two-dimensional (2D) plot profiling as a foundation for advanced statistical modeling and functional prediction in immunofluorescence (IF) analysis. By transforming spatial gradients of IF…
This study evaluates the scalability and real-world applicability of the microwave (MA)-assisted persulfate-formate system for field-scale remediation of chromate-contaminated soils, focusing on process feasibility, material logistics, energy efficiency, and integration…
The efficient storage and separation of acetylene (C₂H₂) are vital for industrial safety and process efficiency, yet remain hindered by the lack of materials that simultaneously offer high uptake capacity…
Urban spontaneous plants—commonly found in vacant lots, road verges, and disturbed soils—are increasingly recognized as bioindicators and potential vectors for environmental contaminants. This study investigated the bioaccumulation and translocation patterns…