Cynomolgus E-Cadherin/Cadherin-1 Protein 2746

Additional Information:
accession A0A2K5V299|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundE-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelial tissues.|molecular weightThe protein has a predicted MW of 61.48 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Cynomolgus E-Cadherin/Cadherin-1 Protein 2746proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceE-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelial tissues.Protein namesCadherin-1 (Epithelial cadherin)Gene namesCDH1,CDH1Mass9541DaFunctionCadherins are calcium-dependent cell adhesion proteins.; E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.Subellular locationCell membrane ; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Membrane ; Single-pass type I membrane protein .Target Relevance information above includes information from UniProt accession: A0A2K5V299The UniProt Consortium|