Biotinylated Mouse OX40/TNFRSF4/CD134 Protein 3401

Additional Information:
express systemHEK293|product tagC-His-Avi|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundTumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.|molecular weightThe protein has a predicted MW of 24.2 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per ug by the LAL method.|Biotinylated Mouse OX40/TNFRSF4/CD134 Protein 3401proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceTumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.Protein namesTumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134)Gene namesTnfrsf4,Tnfrsf4 Ox40 Txgp1Mass10090DaFunctionReceptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).Subellular locationMembrane; Single-pass type I membrane protein.TissuesExpressed in CD4(+) T-cells and in T-helper Th17 cells (at protein level).StructureInteracts with TRAF2, TRAF3 and TRAF5.Target Relevance information above includes information from UniProt accession: P47741The UniProt Consortium|