Human SMOC1 Protein 2341

Additional Information:
accession Q9H4F8|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE|backgroundSPARC-related modular calcium binding 1 (SMOC1) represents a vital member of the SPARC matricellular protein family that regulates cell matrix interaction through binding to cell-surface receptors. SMOC1 silencing suppressed the Ang IIinduced myocardial fibrosis of mouse MFBs through affecting the BMP2/Smad signaling pathway.|molecular weightThe protein has a predicted MW of 46.43 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Human SMOC1 Protein 2341proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceSPARC-related modular calcium binding 1 (SMOC1) represents a vital member of the SPARC matricellular protein family that regulates cell matrix interaction through binding to cell-surface receptors. SMOC1 silencing suppressed the Ang IIinduced myocardial fibrosis of mouse MFBs through affecting the BMP2/Smad signaling pathway.Protein namesSPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1)Gene namesSMOC1,SMOC1Mass9606DaFunctionPlays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation.Subellular locationSecreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.TissuesWidely expressed in many tissues with a strongest signal in ovary. No expression in spleen.Post-translational modificationGlycosylated.Target Relevance information above includes information from UniProt accession: Q9H4F8The UniProt Consortium|