Product Name: p53 (D2H9O) Rabbit mAb (Rodent Specific)#32532
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 29908-03-0
Product: Ademetionine
Specificity Sensitivity: p53 (D2H9O) Rabbit mAb (Rodent Specific) recognizes endogenous levels of total p53 protein.
Species Reactivity: Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala349 of mouse p53 protein.
Background: The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). p53 is phosphorylated at multiple sites in vivo a
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27514406?dopt=Abstract
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