Product Name: TLE1/2/3/4 Antibody#4681
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 158013-42-4
Product: meta-iodoHoechst 33258
Specificity Sensitivity: TLE1/2/3/4 Antibody detects endogenous levels of TLE1, TLE2, TLE3, and TLE4 proteins. Based on homology it should also recognize TLE1 and TLE2 of Zebra fish, TLE2 of Xenopus, and Groucho of Drosophila.
Species Reactivity: Human, Mouse, Monkey, D. melanogaster
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp760 of human TLE1. Antibodies are purified by peptide affinity chromatography.
Background: Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho (1). TLEs contain several WD-repeats implicated in protein-protein interaction (2,3). TLEs are transcriptional co-repressors that bi
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19470727?dopt=Abstract
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