Product Name: Phospho-p70 S6 Kinase (Thr389) (1A5) Mouse mAb#9206
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 56420-45-2
Product: Epirubicin
Specificity Sensitivity: Phospho-p70 S6 Kinase (Thr389) (1A5) Mouse mAb detects endogenous levels of p70 S6 kinase only when phosphorylated at Thr389. This antibody also detects p85 S6 kinase when phosphorylated at the analogous site (Thr412) and possibly S6KII phosphorylated at
Species Reactivity: Human, Mouse, Rat, Monkey, D. melanogaster
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr389 of human p70 S6 kinase.
Background: p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression (1,2). p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5 oligo
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19138051?dopt=Abstract
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