Product Name: Phospho-p130 Cas (Tyr410) Antibody#4011
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 138-39-6
Product: Mafenide
Specificity Sensitivity: Phospho-p130 Cas (Tyr410) Antibody detects endogenous levels of p130 Cas only when phosphorylated at tyrosine 410. The antibody may cross-react with other phosphorylated tyrosines in the substrate domain of p130 Cas and paxillin. The antibody may cross-re
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr410 of human p130 Cas. Antibodies are purified by proteinA and peptide affinity chromatography.
Background: p130 Cas (Crk-associated substrate) is a docking protein containing multiple protein-protein interaction domains. The amino-terminal SH3 domain may function as a molecular switch regulating CAS tyrosine phosphorylation, as it interacts with focal adhesion
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25364905?dopt=Abstract
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