Product Name: Phospho-mTOR (Ser2448) (49F9) Rabbit mAb (IHC Specific)#2976
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry: 1:100
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 55-06-1
Product: 3,3,5-Triiodo-L-thyronine (sodium)
Specificity Sensitivity: Phospho-mTOR (Ser2448) (49F9) Rabbit mAb detects endogenous levels of mTOR protein only when phosphorylated at Ser2448.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR.
Background: The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase (1-3) that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth (4,5). When sufficient nutrients are available, mTOR responds to a phosp
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21339646?dopt=Abstract
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