Product Name: Phospho-TPOR (Tyr626) (D3H7B) Rabbit mAb#12712
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 850140-73-7
Product: Afatinib (dimaleate)
Specificity Sensitivity: Phospho-TPOR (Y626) (D3H7B) Rabbit mAb recognizes endogenous levels of TPOR protein only when phosphorylated at Tyr626. This antibody cross-reacts with a 30 kDa protein of unknown origin. This antibody may cross-react with some tyrosine-phosphorylated pro
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr626 of human TPOR protein.
Background: Thrombopoietin receptor (TPOR, c-Mpl) is a hematopoietic receptor that binds the growth factor, thrombopoietin (TPO), responsible for regulation of platelet production (1-3). Expression of TPOR by megakaryocytes is required for megakaryocyte growth and de
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26330898?dopt=Abstract
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