Product Name: Phospho-TNK1 (Tyr277) (D46E7) Rabbit mAb#5638
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 251456-60-7
Product: M344
Specificity Sensitivity: Phospho-TNK1 (Tyr277) (D46E7) Rabbit mAb detects endogenous levels of TNK1 protein only when the amplified gene product is phosphorylated at Tyr277.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr277 of human TNK1 protein.
Background: Tyrosine kinase non-receptor 1 (TNK1) is related to the Ack1 (TNK2) non-receptor kinase that binds cdc42 and inhibits GTPase activity of this cell cycle regulator. TNK1 is broadly expressed in embryogenic tissues and leukemia cell lines, but is restricted
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19364772?dopt=Abstract
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