Product Name: Phospho-PKCδ/θ (Ser643/676) Antibody#9376
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:50
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 304-20-1
Product: Hydralazine (hydrochloride)
Specificity Sensitivity: Phospho-PKCdelta/theta (Ser643/676) Antibody detects endogenous levels of PKCdelta only when phosphorylated at serine 643, and PKCtheta only when phosphorylated at serine 676. This antibody does not cross-react with the phosphorylated PKC isoforms alpha,
Species Reactivity: Human, Mouse, Rat, Monkey, Xenopus
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser643 of rat PKCdelta. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction (1,2). PKC isoforms belong to three groups based on
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/8598336?dopt=Abstract
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