Product Name: Phospho-PKCα/β II (Thr638/641) Antibody#9375
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 25122-46-7
Product: Clobetasol propionate
Specificity Sensitivity: Phospho-PKC alpha/beta II (Thr638/641) Antibody detects PKC alpha only when phosphorylated at threonine 638 and PKC beta II only when phosphorylated at threonine 641. This antibody also reacts with gamma.
Species Reactivity: Human, Mouse, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr638 of human PKC alpha. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction (1,2). PKC isoforms belong to three groups based on
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22623795?dopt=Abstract
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