Product Name: Phospho-PKA C (Thr197) Antibody#4781
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 356-12-7
Product: Fluocinonide
Specificity Sensitivity: Phospho-PKA C (Thr197) Antibody detects endogenous levels of PKA C (-alpha, -beta and -gamma) only when phosphorylated at Thr197. This antibody does not cross-react with PKA C phosphorylated at other sites.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr197 of PKA C. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The second messenger cyclic AMP (cAMP) activates cAMP-dependent protein kinase (PKA or cAPK) in mammalian cells and controls many cellular mechanisms such as gene transcription, ion transport, and protein phosphorylation (1). Inactive PKA is a heterotetra
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23123290?dopt=Abstract
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