Product Name: Phospho-PFKFB2 (Ser483) (D4R1W) Rabbit mAb#13064
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 57-68-1
Product: Sulfamethazine
Specificity Sensitivity: Phospho-PFKFB2 (Ser483) (D4R1W) Rabbit mAb recognizes endogenous levels of PFKFB2 protein only when phosphorylated at Ser483.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser483 of human PFKFB2 protein.
Background: The bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase or PFKFB) catalyzes the synthesis and degradation of fructose 2,6-bisphosphate and regulates its steady-state level (1,2). Fructose 2,6-bisphosphate activates phosphofruct
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25062696?dopt=Abstract
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