Product Name: Phospho-PDGF Receptor β (Tyr751) (C63G6) Rabbit mAb#4549
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 127-79-7
Product: Sulfamerazine
Specificity Sensitivity: Phospho-PDGF Receptor β (Tyr751) (C63G6) Rabbit mAb detects endogenous levels of PDGF receptor β only when phosphorylated at Tyr751.The antibody may cross-react with activated PDGF receptor α and other protein tyrosine kinases when highly overexpressed.
Species Reactivity: Human, Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr751 of human PDGF receptor β.
Background: Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor α
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24040203?dopt=Abstract
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