Product Name: Phospho-PDGF Receptor β (Tyr751) Antibody#3161
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 58-85-5
Product: Biotin
Specificity Sensitivity: Phospho-PDGF Receptor β (Tyr751) Antibody detects PDGF receptor β only when phosphorylated at Tyr751. The antibody may cross-react with PDGF receptor α when highly overexpressed.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr751 of human PDGF receptor β. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor α
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23993691?dopt=Abstract
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