Product Name: Phospho-PAK4 (Ser474)/PAK5 (Ser602)/PAK6 (Ser560) Antibody#3241
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1261114-01-5
Product: GNF179
Specificity Sensitivity: Phospho-PAK4 (Ser474)/PAK5 (Ser602)/PAK6 (Ser560) Antibody detects endogenous levels of PAK4, PAK5 and PAK6 only when phosphorylated at serine 474, 602, or 560, respectively. The antibody does not cross-react with phosphorylated PAK1, PAK2 or PAK3.
Species Reactivity: Human, Mouse, Guinea Pig
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser474 of human PAK4. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase, and growth factor-induced neurite
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20615987?dopt=Abstract
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