Product Name: Phospho-PAK1 (Ser144)/PAK2 (Ser141) Antibody#2606
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 60-23-1
Product: Cysteamine
Specificity Sensitivity: Phospho-PAK1 (Ser144)/PAK2 (Ser141) Antibody detects endogenous levels of PAK1 and PAK2 only when phosphorylated at serine 144 or serine 141, respectively. This antibody also recognizes Ser139 phosphorylated PAK3 but does not cross-react with phosphorylat
Species Reactivity: Human, Mouse, Guinea Pig
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser144 of human PAK1. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase, and growth factor-induced neurite
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24867636?dopt=Abstract
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