Product Name: Phospho-NPM (Ser4) (D19C1) XP® Rabbit mAb#3520
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 122341-38-2
Product: Temoporfin
Specificity Sensitivity: Phospho-NPM (Ser4) (D19C1) XP® Rabbit mAb detects endogenous levels of NPM only when phosphorylated at Ser4.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues around Ser4 of human NPM. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Nucleophosmin (NPM; also known as B23, numatrin or NO38) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficki
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24890568?dopt=Abstract
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