Product Name: Phospho-Myt1 (Ser83) Antibody#4281
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 713492-66-1
Product: Mcl1-IN-1
Specificity Sensitivity: Phospho-Myt1 (Ser83) Antibody detects endogenous levels of Myt1 only when phosphorylated at serine 83.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser83 of human Myt1. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Entry of all eukaryotic cells into mitosis is regulated by activation of cdc2 kinase. The critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Thr14 (1,2). Phosphorylation at Tyr15 and Th
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24445254?dopt=Abstract
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