Product Name: Phospho-Met (Tyr1349) Antibody#3121
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 802906-73-6
Product: RG7090
Specificity Sensitivity: Phospho-Met (Tyr1349) Antibody detects endogenous levels of Met only when phosphorylated at tyrosine 1349. This antibody may cross-react with activated EGF, PDGF, insulin and FGF receptors.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1349 of human Met. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa α- and 145 kDa β-subunits (1,2). The α-subunit and the amino-terminal region of the β-subunit f
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21438010?dopt=Abstract
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