Product Name: Phospho-Met (Tyr1349) (130H2) Rabbit mAb#3133
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 127243-85-0
Product: H 89
Specificity Sensitivity: Phospho-Met (Tyr1349) (130H2) Rabbit mAb detects endogenous levels of Met only when phosphorylated at tyrosine 1349. This antibody may cross-react with other activated protein tyrosine kinases.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1349 of human Met.
Background: Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa α- and 145 kDa β-subunits (1,2). The α-subunit and the amino-terminal region of the β-subunit f
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20720167?dopt=Abstract
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