Product Name: Phospho-MYPT1 (Ser507) Antibody#3040
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 420126-30-3
Product: Antitumor Compound 1
Specificity Sensitivity: MYPT1 (Ser507) Antibody detects endogenous levels of MYPT1 only when phosphorylated at Ser507.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser507 of human MYPT1. Antibodies are purified using protein A and peptide affinity chromatography.
Background: Protein phosphatase 1 (PP1) is a ubiquitous eukaryotic protein serine/threonine phosphatase involved in the regulation of various cell functions. Substrate specificity is determined by the binding of a regulatory subunit to the PP1 catalytic subunit (PP1c
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23904565?dopt=Abstract
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