Product Name: Phospho-MERIT40 (Ser29) Antibody#12110
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 81732-65-2
Product: Bambuterol
Specificity Sensitivity: Phospho-MERIT40 (Ser29) Antibody recognizes endogenous levels of MERIT40 protein only when phosphorylated at Ser29.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser29 of human MERIT40 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair. BRCA1 forms at least three distinct complexes (BRCA1 A, B, and C
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24492964?dopt=Abstract
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