Product Name: Phospho-MEK1 (Ser298) Antibody#9128
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1380672-07-0
Product: G007-LK
Specificity Sensitivity: Phospho-MEK1 (Ser298) Antibody detects endogenous levels of MEK1 phosphorylated at serine 298. This antibody does not cross-react with phosphorylated MEK2.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser298 of human MEK1. Antibodies are purified by protein A and peptide affinity chromatography.
Background: MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2521629?dopt=Abstract
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