Product Name: Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb#9154
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 126-07-8
Product: Griseofulvin
Specificity Sensitivity: Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb detects endogenous levels of MEK1/2 only when activated by phosphorylation at Ser217/221.
Species Reactivity: Human, Mouse, Rat, Monkey, D. melanogaster
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues around Ser217/221 of human MEK1/2.
Background: MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24911000?dopt=Abstract
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