Product Name: PHGDH (D3D5E) Rabbit mAb (IF Formulated)#32770
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 127-56-0
Product: Sulfacetamide (Sodium)
Specificity Sensitivity: PHGDH (D3D5E) Rabbit mAb recognizes endogenous levels of total PHGDH protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val304 of human PHGDH protein.
Background: Mammalian cells synthesize serine de novo by diverting a portion of the glycolytic intermediate 3-phosphoglycerate into the phosphorylated pathway of serine synthesis. This shift supports anabolism by providing precursors for the biosynthesis of proteins,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27129115?dopt=Abstract
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