Product Name: PDK1 (D37A7) Rabbit mAb#5662
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 5560-59-8
Product: Alverine (citrate)
Specificity Sensitivity: PDK1 (D37A7) Rabbit mAb detects endogenous levels of total PDK1 protein.
Species Reactivity: Human, Mouse, Rat, Hamster, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human PDK1 protein.
Background: Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways (1,2) including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK (3). Through its effects on these kinases, PDK1 is involved in
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17456854?dopt=Abstract
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