Product Name: Notch3 Antibody#2889
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 99592-39-9
Product: Sertaconazole (nitrate)
Specificity Sensitivity: Notch3 Antibody detects endogenous levels of total Notch3 protein. It recognizes the full-length (270 kDa) and the extracellular truncated fragment containing a short extracellular region, the transmembrane domain and the intracellular region (90 kDa).
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro2311 of human notch3. Antibodies were purified by protein A and peptide affinity chromatography.
Background: Notch proteins (Notch1-4) are a family of transmembrane receptors that play important roles in development and the determination of cell fate (1). Mature Notch receptors are processed and assembled as heterodimeric proteins, with each dimer comprised of a
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25557511?dopt=Abstract
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