Product Name: Nicastrin (D65G7) Rabbit mAb#9447
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 521-31-3
Product: Luminol
Specificity Sensitivity: Nicastrin (D65G7) Rabbit mAb recognizes endogenous levels of total nicastrin protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala700 of human nicastrin protein.
Background: Nicastrin is a transmembrane glycoprotein serving as an essential component of the γ-secretase complex (1,2). Nicastrin is physically associated with presenilin and plays an important role in the stabilization and correct localization of presenilin to the
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20683254?dopt=Abstract
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