Product Name: Neurofibromin 1 (D7R7D) Rabbit mAb#14623
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 5985-28-4
Product: Synephrine (hydrochloride)
Specificity Sensitivity: Neurofibromin 1 (D7R7D) Rabbit mAb recognizes endogenous levels of total neurofibromin 1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro360 of human neurofibromin 1 protein.
Background: Neurofibromin is a Ras-specific GTPase activating protein (RasGAP), down-regulating Ras signaling (1). Studies have shown, that mutations in NF1 inhibit its activity, resulting in benign tumors such as neurofibromas, which may form along nerves throughout
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15781651?dopt=Abstract
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