Product Name: NKCC1 Antibody (Rodent Specific)#14581
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 54970-72-8
Product: DHBS
Specificity Sensitivity: NKCC1 Antibody (Rodent Specific) recognizes endogenous levels of total NKCC1 protein in rodents. This antibody also cross-reacts with unidentified proteins at 23 and 42 kDa.
Species Reactivity: Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg77 of mouse NKCC1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The electroneutral cation-chloride-coupled co-transporter (SLC12) gene family comprises bumetanide-sensitive Na+/K+/Cl- (NKCC), thiazide-sensitive Na+/Cl-, and K+/Cl- (KCC) co-transporters. SLC12A1/NKCC2 and SLC12A2/NKCC1 regulate cell volume and maintain
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25663893?dopt=Abstract
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