Product Name: MUC1-C (D5K9I) XP® Rabbit mAb#16564
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:200
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 733767-34-5
Product: NSC 23766
Specificity Sensitivity: MUC1-C (D5K9I) XP® Rabbit mAb recognizes endogenous levels of total MUC1-C protein. This antibody does not detect MUC1-N or full-length (uncleaved) MUC1 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly1192 of human MUC1 protein.
Background: Mucins represent a family of glycoproteins characterized by repeat domains and dense O-glycosylation (1). MUC1 (or mucin 1) is aberrantly overexpressed in most human carcinomas. Increased expression of MUC1 in carcinomas reduces cell-cell and cell-ECM int
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18971331?dopt=Abstract
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