Product Name: MLH1 (D38G9) Rabbit mAb#4256
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 299257
Product: FH1
Specificity Sensitivity: MLH1 (D38G9) Rabbit mAb detects endogenous levels of total MLH1 protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human MLH1 protein.
Background: Mismatch repair (MMR), a conserved process that involves correcting errors made during DNA synthesis, is crucial to the maintenance of genomic integrity. MLH1 is the human homologue of the E. coli MMR gene mutL. MMR requires recognition of a base mismatch
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16330548?dopt=Abstract
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