Product Name: MKK6 (D31D1) Rabbit mAb#8550
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 290297-26-6
Product: Netupitant
Specificity Sensitivity: MKK6 (D31D1) Rabbit mAb recognizes endogenous levels of total MKK6 protein. This antibody does not cross-react with MKK3 or other members of the MKK family.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with recombinant, full-length MKK6 expressed in E. coli.
Background: MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase (1-5). MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAP
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22516460?dopt=Abstract
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