Product Name: MKK3b Antibody#9238
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1001600-56-1
Product: BV6
Specificity Sensitivity: MKK3b Antibody detects endogenous levels of total MKK3b protein. This antibody does not cross-react with MEK1, MEK2, MKK4 or MKK6.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the N-terminal sequence of human MKK3. Antibodies are purified by protein A and peptide affinity chromatogrpahy.
Background: MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase (1-5). MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAP
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24829504?dopt=Abstract
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