Product Name: METTL3 (D2I6O) Rabbit mAb#96391
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 869288-64-2
Product: PF-573228
Specificity Sensitivity: METTL3 (D2I6O) Rabbit mAb recognizes endogenous levels of total METTL3 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu297 of human METTL3 protein.
Background: Methyltransferase-like protein 3 (METTL3) and methytransferase-like protein 14 (METTL14) are the two catalytic subunits of an N6-methyltransferase complex that methylates adenosine residues in RNA (1). Methylation of adenosine residues regulates mRNA spli
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20877725?dopt=Abstract
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