Product Name: MEK1/2 (L38C12) Mouse mAb#4694
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:25
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1351522-05-8
Product: AC710 (Mesylate)
Specificity Sensitivity: MEK1/2 (L38C12) Mouse mAb detects endogenous levels of total MEK1/2 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with full length MEK1/2 proteins.
Background: MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21309724?dopt=Abstract
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