Product Name: MEK1/2 Antibody#9122
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 934162-61-5
Product: A-966492
Specificity Sensitivity: MEK1/2 Antibody detects endogenous levels of total MEK1/2 protein. The antibody does not cross-react with related kinases such as SEK (MKK4), MKK3 or MKK6.
Species Reactivity: Human, Mouse, Rat, Monkey, D. melanogaster
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human MEK1/2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24091663?dopt=Abstract
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