Product Name: Cleaved PARP (Asp214) Antibody (Rat Specific)#9545
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 157283-68-6
Product: Travoprost
Specificity Sensitivity: Cleaved PARP (Asp214) Antibody (Rat Specific) detects endogenous levels of the large fragment of rat PARP1 (89 kDa) resulting from caspase cleavage. The antibody does not recognize full length PARP1 or other PARP isoforms.
Species Reactivity: Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to carboxy-terminal residues surrounding Asp214 in rat PARP. Antibodies are purified by protein A and peptide affinity chromatography.
Background: PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress (1). This protein can be cleaved by many ICE-like caspases in vitro (2,3) and is one of the main cleavage targets of caspase-3 i
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24431212?dopt=Abstract
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